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Christina Chan Selected Research

Palmitates

1/2021Palmitate-Induced IRE1-XBP1-ZEB Signaling Represses Desmoplakin Expression and Promotes Cancer Cell Migration.
2/2014IPAF inflammasome is involved in interleukin-1β production from astrocytes, induced by palmitate; implications for Alzheimer's Disease.
1/2013Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells.
1/2011Synergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cells.
3/2010Synergistic effect of cAMP and palmitate in promoting altered mitochondrial function and cell death in HepG2 cells.
1/2007Hydrogen peroxide and hydroxyl radicals mediate palmitate-induced cytotoxicity to hepatoma cells: relation to mitochondrial permeability transition.

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Christina Chan Research Topics

Disease

24Neoplasms (Cancer)
05/2024 - 10/2008
10Alzheimer Disease (Alzheimer's Disease)
05/2014 - 10/2007
8Hepatocellular Carcinoma (Hepatoma)
10/2015 - 01/2007
7Hepatoblastoma
03/2009 - 01/2007
6Breast Neoplasms (Breast Cancer)
01/2021 - 11/2011
5Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 01/2016
4Sepsis (Septicemia)
01/2023 - 01/2020
4Neoplasm Metastasis (Metastasis)
01/2019 - 01/2014
4Neurodegenerative Diseases (Neurodegenerative Disease)
10/2013 - 10/2007
3Ovarian Neoplasms (Ovarian Cancer)
11/2016 - 08/2015
3Chickenpox
02/2003 - 11/2002
2Dyslipidemias (Dyslipidemia)
01/2024 - 06/2023
2Cardiomyopathies (Cardiomyopathy)
01/2024 - 06/2023
2Lymphoma (Lymphomas)
01/2024 - 12/2023
2COVID-19
01/2023 - 01/2021
2Surgical Wound Infection
01/2021 - 01/2019
2Pneumonia (Pneumonitis)
01/2021 - 01/2014
2Colonic Neoplasms (Colon Cancer)
01/2017 - 01/2016
2Liver Neoplasms (Liver Cancer)
01/2016 - 01/2014
2Chronic Renal Insufficiency
01/2014 - 01/2003
2Obesity
04/2008 - 05/2007
2Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature
01/2008 - 04/2004
1Takotsubo Cardiomyopathy
05/2024
1Temporomandibular Joint Disorders (Temporomandibular Joint Disorder)
01/2024
1Low Back Pain (Lumbago)
01/2024
1Ulcerative Colitis
01/2023
1Hypoxia (Hypoxemia)
01/2023
1Pediatric ulcerative colitis
01/2023
1Systemic Inflammatory Response Syndrome (Sepsis Syndrome)
03/2021
1Bacteremia
01/2021
1Urinary Tract Infections (Urinary Tract Infection)
01/2021
1Intraabdominal Infections
01/2021
1Soft Tissue Infections
01/2021
1Infections
01/2021
1Vascular Diseases (Vascular Disease)
01/2020

Drug/Important Bio-Agent (IBA)

8Nonesterified Fatty Acids (NEFA)IBA
10/2015 - 01/2007
7Proteins (Proteins, Gene)FDA Link
01/2021 - 10/2007
6PalmitatesIBA
01/2021 - 01/2007
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2016 - 05/2007
5Immune Checkpoint InhibitorsIBA
01/2022 - 12/2016
5Fatty Acids (Saturated Fatty Acids)IBA
01/2021 - 05/2007
5PolymersIBA
01/2019 - 01/2016
4Biomarkers (Surrogate Marker)IBA
05/2024 - 11/2011
4MicroRNAs (MicroRNA)IBA
01/2019 - 10/2011
3B7-H1 AntigenIBA
01/2022 - 01/2018
3VaccinesIBA
01/2021 - 11/2002
31-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2017 - 01/2016
3STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2016 - 06/2007
3Amyloid beta-PeptidesIBA
10/2013 - 10/2007
2LipidsIBA
01/2024 - 06/2023
2Fatty Acid DesaturasesIBA
01/2024 - 06/2023
2pyrithione zinc (ZPT)FDA Link
01/2022 - 12/2016
2DNA (Deoxyribonucleic Acid)IBA
01/2022 - 08/2015
2MetalsIBA
11/2019 - 01/2017
2hydroxide ionIBA
01/2017 - 01/2007
2Cisplatin (Platino)FDA LinkGeneric
11/2016 - 08/2015
2Palmitic Acid (Hexadecanoic Acid)IBA
01/2016 - 06/2008
2AntibodiesIBA
01/2016 - 10/2015
2InflammasomesIBA
05/2014 - 02/2014
2tau Proteins (tau Protein)IBA
10/2013 - 07/2010
2CalciumIBA
10/2013 - 11/2011
2Serine C-PalmitoyltransferaseIBA
08/2013 - 10/2011
2Transcription Factors (Transcription Factor)IBA
06/2013 - 03/2013
2Double-Stranded RNA (RNA, Double Stranded)IBA
10/2010 - 04/2009
2eIF-2 Kinase (eIF 2 Kinase)IBA
10/2010 - 04/2009
2STA-21IBA
10/2008 - 06/2007
23-(2-phenylethyl)-4-methylsydnoneIBA
01/2008 - 04/2004
2Chickenpox Vaccine (Vaccine, Varicella)IBA
02/2003 - 01/2003
1TransferasesIBA
05/2024
1Histones (Histone)IBA
05/2024
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
05/2024
1UbiquitinIBA
01/2024
1Ligases (Synthetase)IBA
01/2024
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
12/2023
1BilirubinIBA
01/2023
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2023
1CreatineIBA
01/2023
1Sulfasalazine (Azulfidine)FDA LinkGeneric
01/2023
1Lactic Acid (Lactate)FDA LinkGeneric
01/2023
1Anti-Bacterial Agents (Antibiotics)IBA
01/2023
1SuspensionsIBA
01/2023
1Oxygen (Dioxygen)IBA
01/2023
1remdesivirIBA
01/2023
1IronIBA
01/2022
1dimethylaminomicheliolideIBA
01/2022
1artenimol (dihydroartemisinin)IBA
01/2022
1LactatesIBA
03/2021
1Cadherins (E-Cadherin)IBA
01/2021
1Desmoplakins (Desmoplakin)IBA
01/2021
1TroponinIBA
01/2020

Therapy/Procedure

8Immunotherapy
01/2022 - 01/2016
6Therapeutics
01/2024 - 05/2015
4Radiotherapy
01/2022 - 01/2018
4Photochemotherapy (Photodynamic Therapy)
01/2017 - 01/2016
3Drug Therapy (Chemotherapy)
11/2016 - 11/2011
1Aftercare (After-Treatment)
01/2024
1Cannula
01/2023
1Catheters
01/2021
1Mechanical Ventilators (Ventilator)
01/2021
1Artificial Respiration (Mechanical Ventilation)
01/2020